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The following pages provide all support necessary for unbiased clinical research protocols, methodologies, approved active sham protocols, training, scientific and historical information.

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In the purely scientific field to understand a therapy’s value one trusts only biostatistics and as a norm avoids using direct testimony of individual patients. I completely share this scientific approach, however pain therapy’s main goal is to restore quality of life.

This output is normally expressed by specific tests, but the day I received an email with a picture I realized there is no test capable of expressing in a more straightforward way as the cake a patient brought at the end of her therapy. I cannot find the words to express the emotions I felt. Among other things, the cake arrived on the same day when the site’s first pages were put online. I asked for Mrs. Wall’s permission since her cake has become Scrambler therapy’s official mascot.


I would like to thank Mrs. Walls once again.

Prof. Giuseppe Marineo